Author's response to reviews Title: Visual function and Serous Retinal Detachment in Patients With Branch Retinal Vein Occlusion and Macular Edema: a case series Authors:

manuscript as described on the following pages. In the RETINA study, we divided the macular region into the following nine sections: (1) fovea, 2) superior inner macula, 3) nasal inner macula, 4) inferior inner macula, 5) temporal inner macula, 6) superior outer macula, 7) nasal outer macula, 8) inferior outer macula, and 9) temporal outer macula). We found that retinal sensitivity and thickness were correlated in each section, and multiple regression analysis confirmed this result. In the current study, we divided the macular region into three sections: 1) 1×1 mm (4°×4°) (corresponding to the fovea section in the RETINA study), 2) 3×3 mm (10°×10°) (corresponding to the fovea, superior inner, nasal inner, inferior inner, and temporal inner sections), and 3) 6×6 mm (20°×20°) (corresponding to all 9 sections). Then we investigated whether the retinal sensitivity and thickness of these 3 sections differed between patients with SRD and CME. As stated in the Results, we found that visual acuity was lower in the SRD group than in the CME group, whereas retinal sensitivity was not decreased in the SRD group compared with the CME group. We hope that the revised manuscript adequately addresses your concerns and those of the reviewers, and that our manuscript will now be considered acceptable for publication in your excellent journal. ABSTRACT Comment 1: Background: The first line is very long and need to be re-phrased into 2-3 separate sentences. Line 3 should read as co-exist not co-exists Answer: As suggested, we have shortened this sentence (page 2, lines 2-6 from the top). As suggested, " 15 patients with SRD and 38 patients with CME " has been mentioned in the Results and not in the Methods section (page 2, lines 11 and 12 from the top). Comment 3: Results: Please mention P value if possible along with significance to give a more objective value of your observation. Answer: As suggested, P values have been added to the Results section (page 2, lines 5, 6, and 7 from the bottom). Comment 4: Conclusion: Please also mention that 'SRD does not seem to have an effect on macular function on microperimetry' as per your findings. Answer: Thank you for this helpful suggestion. 'SRD does not seem to have an effect on macular function on microperimetry' has been added to the Conclusion section (page 2, lines 1 and 2 from the bottom).